CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2.
Rac1 is a founding member of the Rho-GTPase family and a key regulator of membrane remodeling. In the context of apoptotic cell corpse engulfment, CED-10/Rac1 acts with its bipartite guanine nucleotide exchange factor, CED-5/Dock180-CED-12/ELMO, in an evolutionarily conserved pathway to promote phag...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2012-01-01
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| Seria: | PLoS Genetics |
| Dostęp online: | http://europepmc.org/articles/PMC3395619?pdf=render |
| Etykiety: |
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