Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome

INTRODUCTION: The lacrimal gland (LG) of the CD25(-)/(-) model of Sjögren’s syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines. The specific contribution of these cytokines to the onset and severity of dacryoadenitis in the CD25(-)/(-) mice has not been evaluate...

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Pubblicato in:Arthritis Res Ther
Autori principali: Bian, Fang, Barbosa, Flavia L, Corrales, Rosa M, Pelegrino, Flavia SA, Volpe, Eugene A, Pflugfelder, Stephen C, de Paiva, Cintia S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392623/
https://ncbi.nlm.nih.gov/pubmed/25889094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0582-9
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