Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

The pro-inflammatory cytokine interleukin-6 (IL-6) in tumor microenvironment has been suggested to promote development and progression of colorectal cancer (CRC). However, the underlying molecular mechanisms remain elusive. In this study, we demonstrate that fos-related antigen-1 (Fra-1) plays a cri...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Liu, Hong, Ren, Guoping, Wang, Tingyang, Chen, Yuexia, Gong, Chaoju, Bai, Yanfeng, Wang, Bo, Qi, Hongyan, Shen, Jing, Zhu, Lijun, Qian, Cheng, Lai, Maode, Shao, Jimin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392608/
https://ncbi.nlm.nih.gov/pubmed/25750173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv017
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