Plasma Pro‐Endothelin‐1 Peptide Concentrations Rise in Chronic Kidney Disease and Following Selective Endothelin A Receptor Antagonism

BACKGROUND: Endothelin 1 (ET‐1) contributes to chronic kidney disease (CKD) development and progression, and endothelin receptor antagonists are being investigated as a novel therapy for CKD. The proET‐1 peptides, endothelin‐like domain peptide (ELDP) and C‐terminal pro‐ET‐1 (CT‐proET‐1), are both p...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Dhaun, Neeraj, Yuzugulen, Jale, Kimmitt, Robert A., Wood, Elizabeth G., Chariyavilaskul, Pajaree, MacIntyre, Iain M., Goddard, Jane, Webb, David J., Corder, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392442/
https://ncbi.nlm.nih.gov/pubmed/25801761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001624
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