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Structural Basis of the Stereospecificity of Bacterial B(12)-dependent 2-Hydroxyisobutyryl-CoA Mutase

Bacterial coenzyme B(12)-dependent 2-hydroxyisobutyryl-CoA mutase (HCM) is a radical enzyme catalyzing the stereospecific interconversion of (S)-3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA. It consists of two subunits, HcmA and HcmB. To characterize the determinants of substrate specificity, we ha...

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Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Kurteva-Yaneva, Nadya, Zahn, Michael, Weichler, M.-Teresa, Starke, Robert, Harms, Hauke, Müller, Roland H., Sträter, Norbert, Rohwerder, Thore
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392272/
https://ncbi.nlm.nih.gov/pubmed/25720495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645689
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