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Structural Basis of the Stereospecificity of Bacterial B(12)-dependent 2-Hydroxyisobutyryl-CoA Mutase
Bacterial coenzyme B(12)-dependent 2-hydroxyisobutyryl-CoA mutase (HCM) is a radical enzyme catalyzing the stereospecific interconversion of (S)-3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA. It consists of two subunits, HcmA and HcmB. To characterize the determinants of substrate specificity, we ha...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392272/ https://ncbi.nlm.nih.gov/pubmed/25720495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645689 |
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