Kit transduced signals counteract erythroid maturation by MAPK-dependent modulation of erythropoietin signaling and apoptosis induction in mouse fetal liver

Signaling by the stem cell factor receptor Kit in hematopoietic stem and progenitor cells is functionally associated with the regulation of cellular proliferation, differentiation and survival. Expression of the receptor is downregulated upon terminal differentiation in most lineages, including red...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Haas, N, Riedt, T, Labbaf, Z, Baßler, K, Gergis, D, Fröhlich, H, Gütgemann, I, Janzen, V, Schorle, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392076/
https://ncbi.nlm.nih.gov/pubmed/25323585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.172
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