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Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer
5-Fluorouracil (5-FU) is chemotherapeutic agent widely used for the treatment of colorectal cancer. Unfortunately, advanced colorectal cancer is often resistance to such chemotherapy and poor outcome. An adaptor protein paxillin (PXN) is phosphorylated at Y31/Y118 (pPXN-Y31/Y118) by Src contributes...
में बचाया:
| में प्रकाशित: | Cell Death Differ |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392075/ https://ncbi.nlm.nih.gov/pubmed/25323586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.170 |
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