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Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer
5-Fluorouracil (5-FU) is chemotherapeutic agent widely used for the treatment of colorectal cancer. Unfortunately, advanced colorectal cancer is often resistance to such chemotherapy and poor outcome. An adaptor protein paxillin (PXN) is phosphorylated at Y31/Y118 (pPXN-Y31/Y118) by Src contributes...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392075/ https://ncbi.nlm.nih.gov/pubmed/25323586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.170 |
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