A Temporal Gate for Viral Enhancers to Co-opt Toll-Like-Receptor Transcriptional Activation Pathways upon Acute Infection

Viral engagement with macrophages activates Toll-Like-Receptors (TLRs) and viruses must contend with the ensuing inflammatory responses to successfully complete their replication cycle. To date, known counter-strategies involve the use of viral-encoded proteins that often employ mimicry mechanisms t...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Kropp, Kai A., Hsieh, Wei Yuan, Isern, Elena, Forster, Thorsten, Krause, Eva, Brune, Wolfram, Angulo, Ana, Ghazal, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391941/
https://ncbi.nlm.nih.gov/pubmed/25856589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004737
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