High-Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets

BACKGROUND: Obesity has been associated with elevated plasma anandamide levels. In addition, anandamide has been shown to stimulate insulin secretion in vitro, suggesting that anandamide might be linked to hyperinsulinemia. OBJECTIVE: To determine whether high-fat diet-induced insulin resistance inc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Woolcott, Orison O., Richey, Joyce M., Kabir, Morvarid, Chow, Robert H., Iyer, Malini S., Kirkman, Erlinda L., Stefanovski, Darko, Lottati, Maya, Kim, Stella P., Harrison, L. Nicole, Ionut, Viorica, Zheng, Dan, Hsu, Isabel R., Catalano, Karyn J., Chiu, Jenny D., Bradshaw, Heather, Wu, Qiang, Bergman, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391925/
https://ncbi.nlm.nih.gov/pubmed/25855974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123558
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