High-Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets

BACKGROUND: Obesity has been associated with elevated plasma anandamide levels. In addition, anandamide has been shown to stimulate insulin secretion in vitro, suggesting that anandamide might be linked to hyperinsulinemia. OBJECTIVE: To determine whether high-fat diet-induced insulin resistance inc...

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Publicat a:PLoS One
Autors principals: Woolcott, Orison O., Richey, Joyce M., Kabir, Morvarid, Chow, Robert H., Iyer, Malini S., Kirkman, Erlinda L., Stefanovski, Darko, Lottati, Maya, Kim, Stella P., Harrison, L. Nicole, Ionut, Viorica, Zheng, Dan, Hsu, Isabel R., Catalano, Karyn J., Chiu, Jenny D., Bradshaw, Heather, Wu, Qiang, Bergman, Richard N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391925/
https://ncbi.nlm.nih.gov/pubmed/25855974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123558
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