Elevated Plasma CXCL12α Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension

RATIONALE: Recent work in preclinical models suggests that signalling via the pro-angiogenic and pro-inflammatory cytokine, CXCL12 (SDF-1), plays an important pathogenic role in pulmonary hypertension (PH). The objective of this study was to establish whether circulating concentrations of CXCL12α we...

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Publicat a:PLoS One
Autors principals: McCullagh, Brian N., Costello, Christine M., Li, Lili, O’Connell, Caroline, Codd, Mary, Lawrie, Allan, Morton, Allison, Kiely, David G., Condliffe, Robin, Elliot, Charles, McLoughlin, Paul, Gaine, Sean
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391833/
https://ncbi.nlm.nih.gov/pubmed/25856504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123709
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