Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

BACKGROUND: Epigenetic changes in DNA methylation could regulate the expression of several allergy-related genes. We investigated whether tolerance acquisition in children with immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA) is characterized by a specific DNA methylation profile of Th2 (IL-...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Berni Canani, Roberto, Paparo, Lorella, Nocerino, Rita, Cosenza, Linda, Pezzella, Vincenza, Di Costanzo, Margherita, Capasso, Mario, Del Monaco, Valentina, D’Argenio, Valeria, Greco, Luigi, Salvatore, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391731/
https://ncbi.nlm.nih.gov/pubmed/25859290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0070-8
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