Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications

BACKGROUND: The proliferating activity of a single leukemia stem cell and the molecular mechanisms for their quiescent property remain unknown, and also their prognostic value remains a matter of debate. Therefore, this study aimed to demonstrate the quiescence property and molecular signature of le...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Won, Eun Jeong, Kim, Hye-Ran, Park, Ra-Young, Choi, Seok-Yong, Shin, Jong Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Szardenings, Michael, Shin, Myung-Geun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391681/
https://ncbi.nlm.nih.gov/pubmed/25881148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1233-x
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