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The NuA4 Complex Promotes Translesion Synthesis (TLS)-Mediated DNA Damage Tolerance
Lesions in DNA can block replication fork progression, leading to its collapse and gross chromosomal rearrangements. To circumvent such outcomes, the DNA damage tolerance (DDT) pathway becomes engaged, allowing the replisome to bypass a lesion and complete S phase. Chromatin remodeling complexes hav...
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| 出版年: | Genetics |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391564/ https://ncbi.nlm.nih.gov/pubmed/25701288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.174490 |
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