Mucosal effects of tenofovir 1% gel

Tenofovir gel is being evaluated for vaginal and rectal pre-exposure prophylaxis against HIV transmission. Because this is a new prevention strategy, we broadly assessed its effects on the mucosa. In MTN-007, a phase-1, randomized, double-blinded rectal microbicide trial, we used systems genomics/pr...

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Pubblicato in:eLife
Autori principali: Hladik, Florian, Burgener, Adam, Ballweber, Lamar, Gottardo, Raphael, Vojtech, Lucia, Fourati, Slim, Dai, James Y, Cameron, Mark J, Strobl, Johanna, Hughes, Sean M, Hoesley, Craig, Andrew, Philip, Johnson, Sherri, Piper, Jeanna, Friend, David R, Ball, T Blake, Cranston, Ross D, Mayer, Kenneth H, McElrath, M Juliana, McGowan, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
Soggetti:
Human Biology and Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391502/
https://ncbi.nlm.nih.gov/pubmed/25647729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04525
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