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DECODING THE INTRINSIC MECHANISM THAT PROHIBITS ALIX INTERACTION WITH ESCRT AND VIRAL PROTEINS
The adaptor protein ALIX links retroviruses to ESCRT machinery during retroviral budding. This function of ALIX requires its interaction with the ESCRT-III component CHMP4 at the N-terminal Bro1 domain and retroviral Gag proteins at the middle V domain. Since cytoplasmic or recombinant ALIX is unabl...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391464/ https://ncbi.nlm.nih.gov/pubmed/20929444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100862 |
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