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Id proteins control growth induction in mammalian cells.

Id1, Id2, and Id3 (HLH462) dimerize with members of the basic helix-loop-helix protein family, but due to the absence of the basic region, the resulting heterodimers cannot bind DNA. Therefore Id-type proteins negatively regulate DNA binding of the basic helix-loop-helix proteins. Here we report tha...

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Autors principals: Barone, M V, Pepperkok, R, Peverali, F A, Philipson, L
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC43914/
https://ncbi.nlm.nih.gov/pubmed/8197168
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