A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites

Next-generation transcriptome sequencing is increasingly integrated with mass spectrometry to enhance MS-based protein and peptide identification. Recently, a breakthrough in transcriptome analysis was achieved with the development of ribosome profiling (ribo-seq). This technology is based on the de...

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Gepubliceerd in:Proteomics
Hoofdauteurs: Koch, Alexander, Gawron, Daria, Steyaert, Sandra, Ndah, Elvis, Crappé, Jeroen, De Keulenaer, Sarah, De Meester, Ellen, Ma, Ming, Shen, Ben, Gevaert, Kris, Van Criekinge, Wim, Van Damme, Petra, Menschaert, Gerben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391000/
https://ncbi.nlm.nih.gov/pubmed/25156699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400180
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