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Targeting cell cycle regulators in hematologic malignancies

Hematologic malignancies represent the fourth most frequently diagnosed cancer in economically developed countries. In hematologic malignancies normal hematopoiesis is interrupted by uncontrolled growth of a genetically altered stem or progenitor cell (HSPC) that maintains its ability of self-renewa...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Aleem, Eiman, Arceci, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390903/
https://ncbi.nlm.nih.gov/pubmed/25914884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00016
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