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Does DNA Exert an Active Role in Generating Cell-Sized Spheres in an Aqueous Solution with a Crowding Binary Polymer?

We report the spontaneous generation of a cell-like morphology in an environment crowded with the polymers dextran and polyethylene glycol (PEG) in the presence of DNA. DNA molecules were selectively located in the interior of dextran-rich micro-droplets, when the composition of an aqueous two-phase...

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Bibliographic Details
Published in:Life (Basel)
Main Authors: Tsumoto, Kanta, Arai, Masafumi, Nakatani, Naoki, Watanabe, Shun N., Yoshikawa, Kenichi
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390863/
https://ncbi.nlm.nih.gov/pubmed/25809964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life5010459
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