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Structural Disorder of Folded Proteins: Isotope-Edited 2D IR Spectroscopy and Markov State Modeling

The conformational heterogeneity of the N-terminal domain of the ribosomal protein L9 (NTL9(1-39)) in its folded state is investigated using isotope-edited two-dimensional infrared spectroscopy. Backbone carbonyls are isotope-labeled ((13)C=(18)O) at five selected positions (V3, V9, V9G13, G16, and...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Baiz, Carlos R., Tokmakoff, Andrei
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390782/
https://ncbi.nlm.nih.gov/pubmed/25863066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.061
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