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A heparin-mimicking reverse thermal gel for controlled delivery of positively charged proteins

Positively charged therapeutic proteins have been used extensively for biomedical applications. However, the safety and efficacy of proteins are mostly limited by their physical and chemical instability and short half-lives in physiological conditions. To this end, we created a heparin-mimicking sul...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Peña, Brisa, Shandas, Robin, Park, Daewon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390447/
https://ncbi.nlm.nih.gov/pubmed/25294242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35345
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