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A heparin-mimicking reverse thermal gel for controlled delivery of positively charged proteins

Positively charged therapeutic proteins have been used extensively for biomedical applications. However, the safety and efficacy of proteins are mostly limited by their physical and chemical instability and short half-lives in physiological conditions. To this end, we created a heparin-mimicking sul...

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Pubblicato in:J Biomed Mater Res A
Autori principali: Peña, Brisa, Shandas, Robin, Park, Daewon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390447/
https://ncbi.nlm.nih.gov/pubmed/25294242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35345
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