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ChIP-nexus: a novel ChIP-exo protocol for improved detection of in vivo transcription factor binding footprints

Understanding how eukaryotic enhancers are bound and regulated by specific combinations of transcription factors is still a major challenge. To better map transcription factor binding genome-wide at nucleotide resolution in vivo, we have developed a robust ChIP-exo protocol called ChIP experiments w...

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Publicat a:Nat Biotechnol
Autors principals: He, Qiye, Johnston, Jeff, Zeitlinger, Julia
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390430/
https://ncbi.nlm.nih.gov/pubmed/25751057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3121
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