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Structural insights into ubiquinone biosynthesis in membranes
Biosynthesis of ubiquinones requires the intramembrane UbiA enzyme, an archetypal member of a superfamily of prenyltransferases that generates lipophilic aromatic compounds. Mutations in eukaryotic superfamily members have been linked to cardiovascular degeneration and Parkinson's disease. To u...
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| Udgivet i: | Science |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390396/ https://ncbi.nlm.nih.gov/pubmed/24558159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1246774 |
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