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Reduced Adolescent-Age Spatial Learning Ability Associated with Elevated Juvenile-Age Superoxide Levels in Complex I Mouse Mutants

Large-scale, heteroplasmic and generally pathogenic mtDNA defects (as induced by defective mitochondrial DNA polymerase, clonal mutations or DNA deletions) are known to negatively impact on life span and can result in apoptosis and tissue loss in, e.g., skeletal muscle or reduce learning abilities....

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Mayer, Johannes, Reichart, Gesine, Tokay, Tursonjan, Lange, Falko, Baltrusch, Simone, Junghanss, Christian, Wolkenhauer, Olaf, Jaster, Robert, Kunz, Manfred, Tiedge, Markus, Ibrahim, Saleh, Fuellen, Georg, Köhling, Rüdiger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390344/
https://ncbi.nlm.nih.gov/pubmed/25853418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123863
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