Proteomic Analysis of the Palmitate-induced Myotube Secretome Reveals Involvement of the Annexin A1-Formyl Peptide Receptor 2 (FPR2) Pathway in Insulin Resistance

Elevated levels of the free fatty acid palmitate are found in the plasma of obese patients and induce insulin resistance. Skeletal muscle secretes myokines as extracellular signaling mediators in response to pathophysiological conditions. Here, we identified and characterized the skeletal muscle sec...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Yoon, Jong Hyuk, Kim, Dayea, Jang, Jin-Hyeok, Ghim, Jaewang, Park, Soyeon, Song, Parkyong, Kwon, Yonghoon, Kim, Jaeyoon, Hwang, Daehee, Bae, Yoe-Sik, Suh, Pann-Ghill, Berggren, Per-Olof, Ryu, Sung Ho
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390267/
https://ncbi.nlm.nih.gov/pubmed/25616869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.039651
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