Emodin Regulates Glucose Utilization by Activating AMP-activated Protein Kinase

AMP-activated protein kinase has been described as a key signaling protein that can regulate energy homeostasis. Here, we aimed to characterize novel AMP-activated kinase (AMPK)-activating compounds that have a much lower effective concentration than metformin. As a result, emodin, a natural anthraq...

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Autors principals: Song, Parkyong, Kim, Jong Hyun, Ghim, Jaewang, Yoon, Jong Hyuk, Lee, Areum, Kwon, Yonghoon, Hyun, Hyunjung, Moon, Hyo-Youl, Choi, Hueng-Sik, Berggren, Per-Olof, Suh, Pann-Ghill, Ryu, Sung Ho
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581390/
https://ncbi.nlm.nih.gov/pubmed/23303186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441477
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