Immune Protection against Trypanosoma cruzi Induced by TcVac4 in a Canine Model

Chagas disease, caused by Trypanosoma cruzi, is endemic in southern parts of the American continent. Herein, we have tested the protective efficacy of a DNA-prime/T. rangeli-boost (TcVac4) vaccine in a dog (Canis familiaris) model. Dogs were immunized with two-doses of DNA vaccine (pcDNA3.1 encoding...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Aparicio-Burgos, José E., Zepeda-Escobar, José A., de Oca-Jimenez, Roberto Montes, Estrada-Franco, José G., Barbabosa-Pliego, Alberto, Ochoa-García, Laucel, Alejandre-Aguilar, Ricardo, Rivas, Nancy, Peñuelas-Rivas, Giovanna, Val-Arreola, Margarita, Gupta, Shivali, Salazar-García, Felix, Garg, Nisha J., Vázquez-Chagoyán, Juan C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390229/
https://ncbi.nlm.nih.gov/pubmed/25853654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003625
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