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Serum-Mediated Activation of Macrophages Reflects TcVac2 Vaccine Efficacy against Chagas Disease

Chagas disease is endemic in Latin America and an emerging infectious disease in the United States. No effective treatments are available. The TcG1, TcG2, and TcG4 antigens are highly conserved in clinically relevant Trypanosoma cruzi isolates and are recognized by B and T cells in infected hosts. D...

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Библиографические подробности
Главные авторы: Gupta, Shivali, Silva, Trevor S., Osizugbo, Jessica E., Tucker, Laura, Spratt, Heidi M., Garg, Nisha J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993374/
https://ncbi.nlm.nih.gov/pubmed/24421046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01186-13
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