A highly conserved program of neuronal microexons is misregulated in autistic brains

Alternative splicing (AS) generates vast transcriptomic and proteomic complexity. However, which of the myriad of detected AS events provide important biological functions is not well understood. Here, we define the largest program of functionally coordinated, neural-regulated AS described to date i...

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Publicado no:Cell
Main Authors: Irimia, Manuel, Weatheritt, Robert J., Ellis, Jonathan, Parikshak, Neelroop N., Gonatopoulos-Pournatzis, Thomas, Babor, Mariana, Quesnel-Vallières, Mathieu, Tapial, Javier, Raj, Bushra, O’Hanlon, Dave, Barrios-Rodiles, Miriam, Sternberg, Michael J.E., Cordes, Sabine P., Roth, Frederick P., Wrana, Jeffrey L., Geschwind, Daniel H., Blencowe, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390143/
https://ncbi.nlm.nih.gov/pubmed/25525873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.035
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