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Beyond Mitophagy: Cytosolic PINK1 as a Messenger of Mitochondrial Health
Significance: Disruptions in mitochondrial homeostasis are implicated in human diseases across the lifespan. Recessive mutations in PINK1, which encodes the mitochondrially targeted PTEN-induced putative kinase 1 (PINK1), cause an autosomal recessive form of Parkinson's disease. As with all kin...
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Опубликовано в: : | Antioxid Redox Signal |
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Главные авторы: | , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Mary Ann Liebert, Inc.
2015
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390087/ https://ncbi.nlm.nih.gov/pubmed/25557302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6206 |
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