Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice

AIMS: Methionine restriction (MR) and hepatic protein tyrosine phosphatase 1B (PTP1B) knockdown both improve hepatic insulin sensitivity by targeting different proteins within the insulin signaling pathway, as well as diminishing hepatic triglyceride content through decreasing hepatic lipogenesis. W...

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Veröffentlicht in:Metabolism
Hauptverfasser: Lees, E. K., Krol, E., Shearer, K., Mody, N., Gettys, T. W., Delibegović, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390031/
https://ncbi.nlm.nih.gov/pubmed/25468142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2014.10.038
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