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Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice

AIMS: Methionine restriction (MR) and hepatic protein tyrosine phosphatase 1B (PTP1B) knockdown both improve hepatic insulin sensitivity by targeting different proteins within the insulin signaling pathway, as well as diminishing hepatic triglyceride content through decreasing hepatic lipogenesis. W...

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Detalhes bibliográficos
Publicado no:Metabolism
Main Authors: Lees, E. K., Krol, E., Shearer, K., Mody, N., Gettys, T. W., Delibegović, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390031/
https://ncbi.nlm.nih.gov/pubmed/25468142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2014.10.038
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