EVI1 promotes tumor growth via transcriptional repression of MS4A3

BACKGROUND: The transcription factor Ecotropic Virus Integration site 1 (EVI1) regulates cellular proliferation, differentiation, and apoptosis, and its overexpression contributes to an aggressive course of disease in myeloid leukemias and other malignancies. Notwithstanding, knowledge about the tar...

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Publicado en:J Hematol Oncol
Autores principales: Heller, Gerwin, Rommer, Anna, Steinleitner, Katarina, Etzler, Julia, Hackl, Hubert, Heffeter, Petra, Tomasich, Erwin, Filipits, Martin, Steinmetz, Birgit, Topakian, Thais, Klingenbrunner, Simone, Ziegler, Barbara, Spittler, Andreas, Zöchbauer-Müller, Sabine, Berger, Walter, Wieser, Rotraud
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389965/
https://ncbi.nlm.nih.gov/pubmed/25886616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0124-6
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