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Autophagic degradation of GZMB/granzyme B: A new mechanism of hypoxic tumor cell escape from natural killer cell-mediated lysis

The crucial issue for defining successful natural killer (NK)-based anticancer therapy is the ability of tumor cells to activate resistance mechanisms leading to escape from NK-mediated killing. It is now well established that such mechanisms are likely evolved under hypoxia in the tumor microenviro...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Viry, Elodie, Baginska, Joanna, Berchem, Guy, Noman, Muhammad Zaeem, Medves, Sandrine, Chouaib, Salem, Janji, Bassam
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389872/
https://ncbi.nlm.nih.gov/pubmed/24248158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26924
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