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HER-2 gene amplification can be acquired as breast cancer progresses
Amplification and overexpression of the HER-2 oncogene in breast cancer is felt to be stable over the course of disease and concordant between primary tumor and metastases. Therefore, patients with HER-2-negative primary tumors rarely will receive anti-Her-2 antibody (trastuzumab, Herceptin) therapy...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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National Academy of Sciences
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC438987/ https://ncbi.nlm.nih.gov/pubmed/15194824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402993101 |
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