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Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes

Bullous pemphigoid (BP) is the most common subepidermal autoimmune blistering skin disease characterized by autoantibodies against the hemidesmosomal proteins BP180 and BP230. The cell stress chaperone heat shock protein 90 (Hsp90) has been implicated in inflammatory responses, and recent evidence s...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Tukaj, Stefan, Grüner, Denise, Zillikens, Detlef, Kasperkiewicz, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389849/
https://ncbi.nlm.nih.gov/pubmed/24796797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0513-8
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