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Inhibitory effects of heat shock protein 90 blockade on proinflammatory human Th1 and Th17 cell subpopulations

BACKGROUND: Heat shock protein 90 (Hsp90), a chaperone that regulates activity of many client proteins responsible for cellular growth, differentiation, and apoptosis, has been proposed as an important clinical and preclinical therapeutic target in a number of malignancies and autoimmune diseases, r...

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Detalhes bibliográficos
Main Authors: Tukaj, Stefan, Zillikens, Detlef, Kasperkiewicz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976086/
https://ncbi.nlm.nih.gov/pubmed/24694060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-11-10
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