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Hsp70 regulates the doxorubicin-mediated heart failure in Hsp70-transgenic mice

The aim of this study was to investigate the potential protective effect of the Hsp70 protein in the cardiac dysfunction induced by doxorubicin (DOX) and the mechanisms of its action. For this purpose, we used both wild-type mice (F1/F1) and Hsp70-transgenic mice (Tg/Tg) overexpressing human HSP70....

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Foilsithe in:Cell Stress Chaperones
Main Authors: Naka K, Katerina, Vezyraki, Patra, Kalaitzakis, Alexandros, Zerikiotis, Stelios, Michalis, Lampros, Angelidis, Charalampos
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389845/
https://ncbi.nlm.nih.gov/pubmed/24748476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0509-4
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