Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks

For many years, there has been uncertainty concerning the reason for Hsp70 translocation to the nucleus and nucleolus. Herein, we propose that Hsp70 translocates to the nucleus and nucleoli in order to participate in pathways related to the protection of the nucleoplasmic DNA or ribosomal DNA from s...

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Bibliographic Details
Main Authors: Kotoglou, Polychronis, Kalaitzakis, Alexandros, Vezyraki, Patra, Tzavaras, Theodore, Michalis, Lampros K., Dantzer, Francoise, Jung, Jae U., Angelidis, Charalampos
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2008
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728274/
https://ncbi.nlm.nih.gov/pubmed/19089598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-008-0093-6
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