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Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective

Physiologically based pharmacokinetic (PBPK) modeling holds great promise for anticipating the quantitative changes of pharmacokinetics in pediatric populations relative to adults, which has served as a useful tool in regulatory reviews. Although the availability of specialized software for PBPK mod...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Yu, Guo, Zheng, Qing-Shan, Li, Guo-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389743/
https://ncbi.nlm.nih.gov/pubmed/25182208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9652-1
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