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Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults

Many physiologic differences between children and adults may result in age-related changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid among other factors determine...

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Detalhes bibliográficos
Main Authors: Fernandez, Eva, Perez, Raul, Hernandez, Alfredo, Tejada, Pilar, Arteta, Marta, Ramos, Jose T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857037/
https://ncbi.nlm.nih.gov/pubmed/24310425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics3010053
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