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Multiplex bisulfite PCR resequencing of clinical FFPE DNA

BACKGROUND: The clinical utility of DNA methylation as a predictive or prognostic biomarker requires scalable resequencing protocols for bisulfite-converted DNA. Key features of any validation method should be adaptability for low- or high-throughput needs and high reproducibility, and should only r...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Korbie, Darren, Lin, Erica, Wall, David, Nair, Shalima S, Stirzaker, Clare, Clark, Sue J, Trau, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389706/
https://ncbi.nlm.nih.gov/pubmed/25861392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0067-3
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