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Histological evaluation of intratumoral myxoma virus treatment in an immunocompetent mouse model of melanoma

Two recombinant myxoma viruses (MYXV expressing a fluorescent protein [MYXV-Tred] and MYXV-Tred encoding murine interleukin-15 [MYXV-IL15]) were evaluated for therapeutic effects in an aggressive B16F10 melanoma model in immunocompetent mice. It was hypothesized that continuous expression of IL-15 w...

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Detalhes bibliográficos
Publicado no:Oncolytic Virother
Main Authors: Doty, Rosalinda A, Liu, Jia, McFadden, Grant, Roy, Edward J, MacNeill, Amy L
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389688/
https://ncbi.nlm.nih.gov/pubmed/25866742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S37971
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