Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells

INTRODUCTION: Type I interferons are pivotal in the activation of autoimmune response in systemic lupus erythematous. However, the pathogenic role of interferon-alpha in patients affected by lupus nephritis remains uncertain. The aim of our study was to investigate the presence of a specific interfe...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Castellano, Giuseppe, Cafiero, Cesira, Divella, Chiara, Sallustio, Fabio, Gigante, Margherita, Pontrelli, Paola, De Palma, Giuseppe, Rossini, Michele, Grandaliano, Giuseppe, Gesualdo, Loreto
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389585/
https://ncbi.nlm.nih.gov/pubmed/25889472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0588-3
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