Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein

INTRODUCTION: The pathophysiology of endotoxemia-induced acute kidney injury (AKI) is characterized by an intense activation of the host immune system and renal resident cells by lipopolysaccharide (LPS) and derived proinflammatory products. However, the occurrence of renal fibrosis in this setting...

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Main Authors: Castellano, Giuseppe, Stasi, Alessandra, Intini, Angelica, Gigante, Margherita, Di Palma, Anna Maria, Divella, Chiara, Netti, Giuseppe Stefano, Prattichizzo, Clelia, Pontrelli, Paola, Crovace, Antonio, Staffieri, Francesco, Fiaccadori, Enrico, Brienza, Nicola, Grandaliano, Giuseppe, Pertosa, Giovanni, Gesualdo, Loreto
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205288/
https://ncbi.nlm.nih.gov/pubmed/25261195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0520-2
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