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Catalytic activation of multimeric RNase E and RNase G by 5′-monophosphorylated RNA

RNase E is an endonuclease that plays a central role in RNA processing and degradation in Escherichia coli. Like its E. coli homolog RNase G, RNase E shows a marked preference for cleaving RNAs that bear a monophosphate, rather than a triphosphate or hydroxyl, at the 5′ end. To investigate the mecha...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jiang, Xunqing, Belasco, Joel G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC438955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15197283/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401382101
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