Genetic Analysis of Disulfide Isomerization in Escherichia coli: Expression of DsbC Is Modulated by RNase E-Dependent mRNA Processing

We designed a selection strategy for the isolation of Escherichia coli mutants exhibiting enhanced protein disulfide isomerase activity. The folding of a variant of tissue plasminogen activator (v-tPA), a protein containing nine disulfide bonds, in the bacterial periplasm is completely dependent on...

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Detalhes bibliográficos
Main Authors: Zhan, Xiaoming, Gao, Junjun, Jain, Chaitanya, Cieslewicz, Michael J., Swartz, James R., Georgiou, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321487/
https://ncbi.nlm.nih.gov/pubmed/14729690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.3.654-660.2004
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